ACS GCI Pharmaceutical Roundtable Publications
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2023
Green Chemistry Articles of Interest to the Pharmaceutical Industry
Marian C. Bryan*, Charlotte Dalton, Alba Díaz-Rodríguez, Jaika Doerfler, Oliver D. Engl, Alejandro Gimenez Molina, Vanessa Harawa, Christopher B. Kelly, Wei Li, Rachel H. Munday, Jan Pawlas, Paul F. Richardson, William J. Smith III, Alan Steven*, Balaram S. Takale, Jack A. Terrett, Daniel S. Treitler, and Mingshuo Zeng., Org. Process Res. Dev. 2023, 27, 4, 563–570. Publication Date: April 4, 2023. https://doi.org/10.1021/acs.oprd.3c00065Green Chemistry Articles of Interest to the Pharmaceutical Industry
Melissa A. Ashley, Miles H. Aukland, Marian C. Bryan*, Megan A. Cismesia, Oliver D. Engl, Pascal S. Engl, Álvaro Enriquez Garcia, Alejandro Gimenez Molina, George Karageorgis, Christopher B. Kelly, Alexandre Leclair, Wei Li, Jan Pawlas, Paul F. Richardson, Alan Steven*, Balaram S. Takale, Mingshuo Zeng, and Yongda Zhang., Org. Process Res. Dev. 2023, 27, 11, 1858-1867.
Publication Date: September 13, 2023. https://doi.org/10.1021/acs.oprd.3c00258A Chemistry in Water Reproducibility Study: Learnings from a Pre-Competitive, Multi-Company Collaboration
Richard Fox, Daniel Bailey, Jennifer Obligacion, Niginia Borlinghaus, Wilfried Braje, Xiaoyong Li, Subha Mukherjee, Adeline Schoen, Timothy Towne, Stella Vukelic., ChemRxiv. 2023.
Publication Date: November 17, 2023. https://doi.org/10.26434/chemrxiv-2023-mgww0 -
2022
Green Chemistry Articles of Interest to the Pharmaceutical Industry
Bryan, M.C.; Dalton, C.; Díaz-Rodríguez, A.; Doerfler, J.; Engl, O.D.; Ferguson, P.; Gimenez Molina, A.; Han. Z. S.; Hasford, J.; Howell, G.P., et. al. Org. Process Res. Dev. 2022, 26(2), 251-262.
https://doi.org/10.1021/acs.oprd.2c00020Importance of Green Chemistry and Sustainable Chemistry in the Chemical Laboratory
Colberg, J.; Hii, K. K.; Koenig, S. ACS Sustain. Chem. Eng. 2022, 10(26), 8239-8241.
https://doi.org/10.1021/acssuschemeng.2c03306Green Chemistry Articles of Interest to the Pharmaceutical Industry
Bryan, M.C.; Dalton, C.; Doerfler, J.; Engl, O.D.; Ferguson, P.; Gimenez Molina, A.; Harawa, V.; Hasford, J.; Howell, G.P., Kelly, C.B.; et. al. Org. Process Res. Dev. 2022, 26(9), 2550-2559.
https://doi.org/10.1021/acs.oprd.2c00274Green and Sustainable Metrics: Charting the Course for Green-By-Design Small Molecule API Synthesis
Rose, H.B.; Kosjek, B.; Armstrong, B.M.; Robaire, S.A. Curr. Opin. Green Sustain. Chem. 2022, 5, 100324.
https://doi.org/10.1016/j.crgsc.2022.100324Streamlined Life Cycle Assessment of Single Use Technologies in Biopharmaceutical Manufacture
Budzinski, K.; Constable, D.; D’Aquila, D.; Smith, P.; Madabhushi, S.R.; Whiting, A.; Costelloe, T.; Collins, M. New. Biotech. 2022, 68, 28-36.
https://doi.org/10.1016/j.nbt.2022.01.002
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2021
Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Andrews, B. I.;* Firoz, D. A.; Brueggemeier, S. B.; Diorazio L. J; Koenig, S. G.; Kopach, M.; Lee, H.; Olbrich, M. and Watson, A. J. Org. Chem. 2021, 86, 1, 49–61.
https://doi.org/10.1021/acs.joc.0c02291Green Chemistry Articles of Interest to the Pharmaceutical Industry
Dalton, C.; Diorazio, L. J.; Doerfler, J.; Engl, O. L.; Han, Z. S.; Howell, G. P.; Latham, J.; Li, W.; McLaws, M.; Munday, R. H.; Navarro, A.; Parmentier M.; Pawlas, J.; Richardson, P.; Roiban, G-D.; Steven, A.*; Terrett, J. A.; Treitler, D.S.; and Zeng, M. Org. Process Res. Dev. 2021, 25, 4, 703–712.
https://doi.org/10.1021/acs.oprd.1c0006Manufacturing Mass Intensity: 15 Years of Process Mass Intensity and Development of the Metric into Plant Cleaning and Beyond
Benison, C.*; Payne, P. Curr. Res. Chem. Green Sustain. Chem.
https://doi.org/10.1016/j.crgsc.2021.100229Green Chemistry Articles of Interest to the Pharmaceutical Industry
Bryan M. C.*, Dalton, C.; Diorazio, L. J.; Doerfler, J.; Doyle, L. M.; Engl, O. D.; Gimenez Molina, A.; Han, Z. S.; Hosford, J.; Howell, G. P.; Hutchby, M.; Latham, J.; Li, W.; Munday, R. H.; Navarro, A.; Parmentier, M.; Pawlas, J.; Richardson, P. F.; Steven, A.;* Terrett, J. A. and Zeng, M. Org. Process Res. Dev. 2021, 25, 10, 2167–2176.
https://doi.org/10.1021/acs.oprd.1c00352Making Sustainability Assessment Accessible: Tools Developed by the ACS Green Chemistry Institute Pharmaceutical Roundtable
Diorazio, L. J.; Richardson, R. F.; Sneddon, H.; Moores, A.; Briddell, C. and Martinez, I.* ACS Sustainable Chem. Eng. 2021, 9, 50, 16862–16864.
https://doi.org/10.1021/acssuschemeng.1c07651Improved iGAL 2.0 Metric Empowers Pharmaceutical Scientists to Make Meaningful Contributions to United Nations Sustainable Development Goal 12
Roschangar, F.*; Li, J.; Zhou, Y.; Aelterman, W.; Borovika, A.; Colberg, J.; Dickson, D.; Gallou, F.; Hayler, J.D.; Koenig, S.G.; Kopach, M.E.; Kosjek, B.; Leahy, D.; O’Brien, E.; Smith, A.G.; Henry, M.; Cook, J. and Sheldon, R. A. ACS Sustainable Chem. Eng. 2021, ASAP. https://pubs.acs.org/doi/10.1021/acssuschemeng.1c01940 -
2020
Green Chemistry Articles of Interest to the Pharmaceutical Industry; Marie-Gabrielle Braun, Oliver Engl, Kenneth Fraunhoffer, John Hayler, Matthew Hickey, Jonathan Latham, Lucie E. Lovelle, Mark McLaws, Paul Richardson, Philipp C. Roosen, Alan Steven, Jack A. Terrett, Timothy White, Jingjun Yin. Org. Process Res. Dev. 2020, 24, 6, 897–908. DOI: 10.1021/acs.oprd.0c00154
Green Chemistry Articles of Interest to the Pharmaceutical Industry; Alba Diaz Rodriguez, Charlotte Dalton, Louis Diorazio, Jaika Doerfler, Oliver D. Engl, Matthew Hickey, Gareth Howell, Marc Hutchby, Jonathan Latham, Wei Li, Rachel Munday, Paul Richardson, Philipp C. Roosen, Alan Steven, Jack A. Terrett, Daniel S. Treitler, Timothy White, and Mingshuo Zeng. Org. Process Res. Dev. 2020, 24, 11, 2394-2406. DOI: 10.1021/acs.oprd.0c00456
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2019
A Green Chemistry Continuum for a Robust and Sustainable Active Pharmaceutical Ingredient Supply Chain; Stefan G. Koenig, Cisco Bee, Alina Borovika, Christiana Briddell, Juan Colberg, Guy R. Humphrey, Michael E. Kopach, Isamir Martinez, Sudhir Nambiar, Scott V. Plummer, Seth D. Ribe, Frank Roschangar, Jeremy P. Scott, Helen F. Sneddon. ACS Sustainable Chem. Eng. 2019, 7, 16937−16951. DOI: 10.1021/acssuschemeng.9b02842
Bringing Macrolactamization Full Circle: Self-Cleaving Head-to-Tail Macrocyclization of Unprotected Peptides via Mild N-Acyl Urea Activation; Christine A. Arbour, Kayla J. Belavek, Rooha Tariq, Subha Mukherjee, Janine K. Tom, Albert Isidro-Llobet, Michael E. Kopach, Jennifer L. Stockdill.
J. Org. Chem. 2019, 84(2), 1035-1041. DOI: 10.1021/acs.joc.8b02418Green Chemistry Articles of Interest to the Pharmaceutical Industry, Issue 23; Marie-Gabrielle Braun, John Hayler, Andrew Parsons, Alba Díaz-Rodríguez, Matthew Hickey, Paul Richardson, Louis Diorazio, Lucie Lovelle, Doru Roiban, Kenneth Fraunhoffer, Mark McLaws, Alan Steven. Org. Process Res. Dev. 2019, 23, 6, 1118-1133. DOI: 10.1021/acs.oprd.9b00158
Green Chemistry Articles of Interest to the Pharmaceutical Industry, Issue 24; Marie-Gabrielle Braun, John Hayler, Andrew Parsons, Alan Steven, Jonathan Latham, Matthew Hickey, Paul Richardson, Jack A. Terrett, Louis Diorazio, Lucie Lovelle, Doru Roiban, Timothy White, Kenneth Fraunhoffer, Mark McLaws, Philipp C. Roosen, Jingjun Yin. Org. Process Res. Dev. 2019, 23, 2287-2301. DOI: 10.1021/acs.oprd.9b00450
Introduction of a process mass intensity metric for biologics; Kristi Budzinski, Megan Blewis, Philip Dahlin, Daniel D’Aquila, Julia Esparza, Jack Gavin, Sa V. Ho, Clarice Hutchens, David Kahn, Stefan G. Koenig, Robert Kottmeier, Jeff Millard, Matt Snyder, Brad Stanard, Lixin Sun. New Biotechnology. 2019, 49, 37-42. DOI: 10.1016/j.nbt.2018.07.005.
Making the move towards modernized greener separations: introduction of the analytical method greenness score (AMGS) calculator; Michael B. Hicks, William Farrell, Christine Aurigemma, Laurent Lehmann, Lauren Weisel, Kelly Nadeau, Heewon Lee, Carol Moraff, Mengling Wong, Yun Huangh, Paul Ferguson. Green Chem., 2019 ,21, 1816-1826. DOI: 10.1039/C8GC03875A
Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production; Albert Isidro-Llobet, Martin N. Kenworthy, Subha Mukherjee, Michael E. Kopach, Katarzyna Wegner, Fabrice Gallou, Austin G. Smith, Frank Rrochangar. J. Org. Chem. 2019, 84(8), 4615-4628. DOI: 10.1021/acs.joc.8b03001
The PMI Predictor – a Web App Enabling Green-by-Design Chemical Synthesis; A. Borovika, J. Albrecht, J. Li, A. S. Wells, C. Briddell, B. R. Dillion, L. J. Diorazio, J. R. Gage, F. Gallou, S. G. Koenig, M. E. Kopach, D. K. Leahy, I. Martinez, M. Olbrich, J. L. Piper, F. Roschangar, E. Sherer, M. D. Eastgate. ChemRxiv, Preprint 1/16/2019
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2018
Green Chemistry Articles of Interest to the Pharmaceutical Industry; Org. Process Rev. Dev., 2018, 22, (12), 1699-1711, DOI:10.1021/acs.oprd.8b00363
Evaluating the Impact of a Decade of Funding from the Green Chemistry Institute Pharmaceutical Roundtable; Org. Process Rev. Dev., 2018, 22, (10), 1344-1359, DOI:10.1021/acs.oprd.8b00237
Green Chemistry Articles of Interest to the Pharmaceutical Industry; Org. Process Rev. Dev., 2018, 22, (612), 667-680, DOI:10.1021/acs.oprd.8b00056
Inspiring process innovation via an improved green manufacturing metric: iGAL; Green Chem., 2018, 10, 2206-2211, DOI:10.1039/C8GC00616D
Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited.
Marian C. Bryan, Peter J. Dunn, David Entwistle, Fabrice Gallou, Stefan G. Koenig, John D. Hayler, Matthew R. Hickey, Shaun Hughes, Michael E. Kopach, Gerard Moine, Paul Richardson, Frank Roachangar, Alan Steven, Frans J. Weiberth.
Green. Chem. 2018, 20, 5082-5103. DOI: 10.1039/C8GC01276H -
2017
Sustainable Practices in Medicinal Chemistry Part 2: Green by Design
J. Med. Chem. 2017, 60, 5955-5968. DOI: 10.1021/acs.jmedchem.6b01837Green Chemistry Articles of Interest to the Pharmaceutical Industry
Org. Process Res. Dev. 2017, 21 (10), 1464-1477. DOI: 10.1021/acs.oprd.7b00292Green Chemistry Articles of Interest to the Pharmaceutical Industry
Marian C. Bryan, Louis Diorazio, Zhongbo Fei, Kenneth Fraunhoffer, John Hayler, Matthew Hickey, Shaun Hughes, Luke Humphreys, Paul Richardson, Markus Schober, Alan Steven, Timothy White, Stijn Wuyts, Jingjun Yin. Org. Process Res. Dev. 2017, 21 (2), 153–164. DOI: 10.1021/acs.oprd.7b00014A Deeper Shade of Green: Inspiring Sustainable Drug Manufacturing
Green Chem., 2017, 19, 281-285. DOI:10.1039/C6GC02901A -
2016
Towards a More Holistic Framework for Solvent Selection
Louis J. Diorazio, David R. J. Hose, Neil K. Adlington. Org. Process Res. Dev. 2016, 20 (4), 760–773. DOI: 10.1021/acs.oprd.6b00015Green Chemistry Articles of Interest to the Pharmaceutical Industry
Rakeshwar Bandichhor, Apurba Bhattacharya, Marian C. Bryan, Louis Diorazio, Peter Dunn, Kenneth Fraunhoffer, Fabrice Gallou, John Hayler, Matthew Hickey, Luke Humphreys, Paul Richardson, Gheorghe-Doru Roiban, Timothy White, Stijn Wuyts, Jingjun Yin. Org. Process Res. Dev. 2016, 20 (4), 707–717. DOI:10.1021/acs.oprd.6b00042Green Chemistry Articles of Interest to the Pharmaceutical Industry
Rakeshwar Bandichhor, Apurba Bhattacharya, Marian C. Bryan, Andrew Cosbie, Alba Díaz-Rodríguez, Louis Diorazio, Zhongbo Fei, Kenneth Fraunhoffer, John Hayler, Matthew Hickey, Luke Humphreys, Paul Richardson, Scott Roberts, Timothy White, Stijn Wuyts, Jingjun Yin. Org. Process Res. Dev. 2016, 20 (7), 1118–1132. DOI: 10.1021/acs.oprd.6b00174 -
2014
Green Chemistry Articles of Interest to the Pharmaceutical Industry
Rakeshwar Bandichhor, Apurba Bhattacharya, Louis Diorazio, Peter Dunn, Kenneth Fraunhoffer, Fabrice Gallou, John Hayler, Matthew Hickey, Bill Hinkley, Luke Humphreys, Bernard Kaptein, Suju Mathew, Paul Richardson, Timothy White, Stijn Wuyts, Jingjun Yin. Org. Process Res. Dev. 2014, 18 (12), 1602-1613. DOI: 10.1021/op500345yGreen Chemistry Articles of Interest to the Pharmaceutical Industry
Rakeshwar Bandichhor, Apurba Bhattacharya, Louis Diorazio, Peter Dunn, Kenneth Fraunhoffer, Fabrice Gallou, John Hayler, Matthew Hickey, Bill Hinkley, David Hughes, Luke Humphreys, Bernard Kaptein, Suju Mathew, Lynnette Oh, Paul Richardson, Timothy White, Stijn Wuyts. Org. Process Res. Dev. 2014, 18 (7), 863-874. DOI: 10.1021/op500167ySustainable Chromatography (an oxymoron?)
Emily A. Peterson, Barry Dillon, Izzat T. Raheem, Paul Richardson, Daniel Richter, Rachel Schmidt, and Helen F. Sneddon. Green Chem. July 14, 2014 (web), DOI: 10.1039/C4GC00615A -
2013
2013 Year in Review
Highlights recent accomplishments of the ACS GCI Pharmaceutical Roundtable.3rd Annual ACS GCI Roundtable Poster Reception Abstracts
June 19, 2013, North Bethesda, MD, USA.Expanding the Boundaries: Developing a Streamlined Tool for Eco-Footprinting of Pharmaceuticals
Concepción Jiménez-González, Caleb Ollech, William Pyrz, David Hughes, Quirinus B. Broxterman, and Neil Bhathela. Org. Process Res. Dev. 2013, 17 (2), 239–246. Publication Date (Web): January 3, 2013 (Article), DOI: 10.1021/op3003079Filling Gaps During Carbon Footprint Studies to Design Green Pharmaceuticals
Go with the Flow
Juan Colberg, Stefan Koenig, David Leahy, and Peter Poechlauer. Innovations in Pharmaceutical Technology, 2013, Issue 46, 52-55.Green Chemistry Articles of Interest to the Pharmaceutical Industry
Rakeshwar Bandichhor, Apurba Bhattacharya, Louis Diorazio, Peter Dunn, Kenneth Fraunhoffer, Fabrice Gallou, John Hayler, Matthew Hickey, Bill Hinkley, David Hughes, Luke Humphreys, Bernard Kaptein, Suju Mathew, Lynnette Oh, Paul Richardson, Timothy White, Stijn Wuyts. Org. Process Res. Dev. 2013, 17 (11), 1394–1405. DOI: 10.1021/op400263aGreen Chemistry Articles of Interest to the Pharmaceutical Industry
Rakeshwar Bandichhor, Apurba Bhattacharya, Louis Diorazio, Peter Dunn, Kenneth Fraunhoffer, Fabrice Gallou, John Hayler, Matthew Hickey, William Hinkley, David Hughes, Luke Humphreys, Bernard Kaptein, Suju Mathew, Thomas Rammeloo, Paul Richardson, Timothy White. Org. Process Res. Dev. 2013, 17 (4), 615–626. DOI: 10.1021/op4000434Pharmaceutical Roundtable Study Demonstrates the Value of Continuous Manufacturing in the Design of Greener Processes
Peter Poechlauer, Juan Colberg, Elizabeth Fisher, Michale Jansen, Martin D. Johnson, Stefan G. Koenig, Michael Lawler, Thomas Laporte, Julie Manley, Benjamin Martin, and Ann O’Kearney-McMullan. Org. Process Res. Dev. 2013, 17 (12), 1472-1478. DOI: 10.1021/op400245sSeven Important Elements for an Effective Green Chemistry Program: An IQ Consortium Perspective
David K. Leah; John L. Tucker; Ingrid Mergelsberg; Peter J. Dunn; Michael E. Kopach; and Vikram C. Purohit. Org. Process Res. Dev. 2013, 17, 1099−1109. DOI: /10.1021/op400192hSustainable Practices in Medicinal Chemistry: Current State and Future Directions
Bryan, Marian C.; Dillon, Barry; Hamann, Lawrence G.; Hughes, Gregory J.; Kopach, Michael E.; Peterson, Emily A.; Pourashraf, Meharnez; Raheem, Izzat; Richardson, Paul; Richter, Daniel; Sneddon, Helen. J. Med. Chem. [online early access] DOI: 10.1021/jm400250p. Published Online: April 15, 2013. -
2012
Continuous Processing in the Manufacture of Active Pharmaceutical Ingredients and Finished Dosage Forms: An Industry Perspective
Peter Poechlauer, Julie Manley, Rinus Broxterman, Björn Gregertsen, and Mats Ridemark. Org. Process Res. Dev. 2012, 16 (10), 1586–1590. Publication Date (Web): September 18, 2012 (Concept Article), DOI: 10.1021/op300159yGreen Chemistry Articles of Interest to the Pharmaceutical Industry
L. Amarnath, Ian Andrews, Rakeshwar Bandichhor, Apurba Bhattacharya, Peter Dunn, John Hayler, William Hinkley, Nicole Holub, David Hughes, Luke Humphreys, Bernard Kaptein, Hare Krishnen, Kurt Lorenz, SujuMathew, G. Nagaraju, Thomas Rammeloo, Paul Richardson, Lijun Wang, Andrew Wells, Timothy White. Org. Process Res. Dev. 2012, 16 (4), 535–544. DOI: 10.1021/op300068dGreen Chemistry Articles of Interest to the Pharmaceutical Industry
Rakeshwar Bandichhor , Apurba Bhattacharya, Louis Diorazio, Peter Dunn, Kenneth Fraunhoffer, Fabrice Gallou, John Hayler, Matthew Hickey, Bill Hinkley, David Hughes, Luke Humphreys, Bernd Janocha, Bernard Kaptein, Suju Mathew, Thomas Rammeloo, Paul Richardson, Timothy White. Org. Process Res. Dev. 2012, 16 (12), 1887–1896. DOI: 10.1021/op300251dGreener Journals
Stephen K. Ritter. Chemical & Engineering News. 90(5), January 30, 2012Green Chemistry is Good Process Chemistry
Trevor Laird (Editor). Org. Process Res. Dev. 2012, 16 (1), 1–2. DOI: 10.1021/op200366yPharma Strives for Green Goals
Ann M. Thayer. Chemical & Engineering News. 90(22), May 28, 2012Solvent Choices and Sustainable Chemistry
Guido M. Kemeling. ChemSusChem. December 3, 2012, 5(12), 291-2292. DOI:10.1002/cssc.201200873Use of the Electronic Laboratory Notebook to Facilitate Green Chemistry Within the Pharmaceutical Industry
Michael E. Kopach, Emily A. Reiff. Future Medicinal Chemistry. July 2012, 4(11), 1395-1398. DOI: 10.4155/fmc.12.78 -
2010
Green Chemistry Articles of Interest to the Pharmaceutical Industry
Ian Andrews, Jian Cui, Leo Dudin, Peter Dunn, John Hayler, Bill Hinkley, David Hughes, Bernard Kaptein, Kurt Lorenz, Suju Mathew, Thomas Rammeloo, Lijun Wang, Andrew Wells, Timothy Donald White. Org. Process Res. Dev. 2010, 14 (4), 770–780. DOI: 0.1021/op100116sGreen Chemistry Articles of Interest to the Pharmaceutical Industry
Ian Andrews, Jian Cui, Jimmy DaSilva, Leo Dudin, Peter Dunn, John Hayler, Bill Hinkley, David Hughes, Bernard Kaptein, Kurt Lorenz, Suju Mathew, Thomas Rammeloo, Lijun Wang, Andrew Wells, Timothy White, Fuyao Zhang. Org. Process Res. Dev. 2010,14 (1), 19–29. DOI: 10.1021/op900295s -
2009
Green Chemistry Articles of Interest to the Pharmaceutical Industry
Ian Andrews, Jian Cui, Jimmy DaSilva, Leo Dudin, Peter Dunn, John Hayler, Bill Hinkley, David Hughes, Bernard Kaptein, Stanley Kolis, Kurt Lorenz, Suju Mathew, Thomas Rammeloo, Lijun Wang, Andrew Wells, Timothy White, Chaoyu Xie, Fuyao Zhang. Org. Process Res. Dev. 2009, 13 (3), 397–408. DOI: 10.1021/op900082k -
2008
Collaboration to Deliver a Solvent Selection Guide to the Industry
Green Chemistry Articles of Interest to the Pharmaceutical Industry
Stephen Challenger, Leo Dudin, Jimmy DaSilva, Peter Dunn, Tom Govaerts, John Hayler, Bill Hinkley, Yannis Houpis, Thomas Hunter, Lisa Jellet, John L. LeazerJr., Kurt Lorenz, Suju Mathew, Thomas Rammeloo, Ravinder Sudini, Zonghui Wan, Chris Welch, Andrew Wells, Jennifer Vance, Chaoyu Xie, Fuyao Zhang. Org. Process Res. Dev. 2008, 12 (5), 807–816. DOI: 10.1021/op800175p -
2007
Key Green Chemistry Research Areas: A Perspective from Pharmaceutical Manufacturers
David J. C. Constable, Peter J.Dunn, John D. Hayler, Guy R. Humphrey, Johnnie L Jr. Leazer, Russell J. Linderman, Kurt Lorenz, Julie Manley, Bruce A. Pearlman, Andrew Wells, Aleksey Zaksh, Tony Y. Zhangf. Green Chem. 2007, 9, 411-420. DOI: 10.1039/B703488CKey Green Chemistry Research Areas: A Perspective from Pharmaceutical Manufacturers
Lessons Learned Through Measuring Green Chemistry Performance